LSD1 anticorps (AA 301-400) (HRP)

N° du produit ABIN1711723

Cet anticorps Lapin Polyclonal détecte spécifiquement LSD1 dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour LSD1 anticorps (AA 301-400) (HRP) (ABIN1711723)

Antigène: LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LSD1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA

Détail du produit anti-LSD1 anticorps (HRP)

Épitope: AA 301-400

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human KDM1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur LSD1

Antigène: LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Autre désignation: KDM1

Sujet:

Synonyms: Amine oxidase flavin containing domain 2, Amine oxidase flavin containing domain 2, Amine oxidase flavin containing domain protein 2, AOF 2, AOF2, BHC110, BRAF35 HDAC complex protein BHC110, BRAF35-HDAC complex protein BHC110, FAD binding protein BRAF35 HDAC complex, 110 kDa subunit, Flavin containing amine oxidase domain containing protein 2, Flavin-containing amine oxidase domain-containing protein 2, KDM 1, Kdm1a, KDM1A_HUMAN, KIAA0601, LSD 1, LSD1, Lysine K specic demethylase 1, Lysine K specic demethylase 1A, Lysine specic histone demethylase 1, Lysine specic histone demethylase 1A, Lysine-specic histone demethylase 1, Lysine-specic histone demethylase 1A.

Background: Gene activation and repression is specifically regulated by histone methylation status at distinct lysine residues. Lysine specific demethylase 1 (KDM1/LSD1) is a long-sought histone demethylase that specifically demethylates mono and di methyl histone H3 at K4 and K9. Thus KDM1 is a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor.

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, L'effet Warburg